Development of segmental superficial actinic porokeratosis during immunosuppressive therapy for pemphigus vulgaris.

© 2010 The Authors. doi: 10.2340/00015555-0800 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Porokeratosis (PK) is a heterogeneous group of hereditary or acquired disorders of keratinization with a broad clinical spectrum and various aetiologies. Common to all PK is the typical histological feature of a cornoid lamella, which corresponds to the hyperkeratotic rim of slowly centrifugal spreading lesions (1). Several subtypes of PK have been distinguished based on size, localization and number of lesions. However, porokeratosis of Mibelli (PKM) and disseminated superficial actinic porokeratosis (DSAP) are the most common clinically encountered subtypes.